Archived COVID-19 Resources for Clinicians

Academic Centers, Hospitals, and Community Practices

• Brigham and Women's Hospital (COVID-19 Critical Care Clinical Guidelines)
• Seattle Cancer Care Alliance (patient screening and testing tools, PPE donning and doffing videos, telehealth FAQs)
• University of Washington (Screening and testing algorithms, policies and procedures)

Archived Frequently Asked Clinical Questions

Treatments and Prevention

• General Principles of COVID-19 Vaccines for Immunocompromised Patients (Version 6.1; last April 14, 2022)
• COVID-19 Therapies: Monoclonal Antibodies, Convalescent Plasma and Medications (Version 9.2; last updated April 7, 2022)
• Prevention of COVID-19 in Immunocompromised Patients With Hematologic Conditions (Version 2; last updated April 6, 2023)

Malignant Topics

• COVID-19 and Aggressive Non-Hodgkin Lymphoma (Version 6.0; last updated April 1, 2022)
• COVID-19 and Acute Lymphoblastic Leukemia - Adult (Version 2.1; last updated January 22, 2021)
• COVID-19 and Acute Lymphoblastic Leukemia - Pediatric (Version 3.0; last updated January 29, 2021)
• COVID-19 and Acute Myeloid Leukemia (Version 1.5; last reviewed January 19, 2022)
• COVID-19 and Chronic Lymphocytic Leukemia (Version 4.1; last updated February 2, 2021)
• COVID-19 and Chronic Myeloid Leukemia (Version 3.0; last updated September 28, 2021)
• COVID-19 and Hematopoietic Cell Transplantation (Version 2.0; last updated April 1, 2022)
• COVID-19 and Hodgkin Lymphoma (Version 6.0; last updated April 1, 2022)
• COVID-19 and Indolent Lymphomas (Version 6.0; last updated April 1, 2022)
• COVID-19 and Myelodysplastic Syndromes (Version 4.2; last updated May 17, 2021)
• COVID-19 and Myeloproliferative Neoplasms (Version 6.0; last updated September 3, 2021)
• COVID-19 and Multiple Myeloma (Version 2.1; last updated January 22, 2021)

Non-malignant Topics

• COVID-19 and Aplastic Anemia (Version 3.0; last updated May 6, 2021)
• COVID-19 and Immune Thrombocytopenic Purpura (Version 6.1; last updated April 21, 2021)
• COVID-19 and Sickle Cell Disease (Version 6.1; last updated May 28, 2021)
• COVID-19 and Thalassemia (Version 2.1; last updated January 19, 2022)
• COVID-19 and Thrombotic Thrombocytopenic Purpura (Version 3.3; last updated April 4, 2022)
• COVID-19 and VTE/Anticoagulation (Version 14.0; last updated February 2, 2022)

Clinical Laboratory Topics

• COVID-19 and aPL Antibodies (Version 1.1; last updated February 2, 2022)
• COVID-19 and D-dimer (Version 1.0; last updated April 20, 2020)
• COVID-19 and Viscoelastic Hemostasis Assays (Version 2.0; last updated February 25, 2021)

Clinical FAQ Resources from Other Societies

• ISA recommendations on the management of patients with systemic amyloidosis during the COVID-19 pandemic

COVID-19 Treatments

Guidance About COVID-19 Treatment

• Assessment of Evidence for COVID-19 related treatments
• Tables of COVID-19 drug-drug interactions
• NIH COVID treatment guidance
• CDC Clinician On-Call Center
  24-hour access to CDC clinicians to answer COVID-19 questions.

Clinical Trials and Studies

• COVID-19 Clinical Trial Tracker
• ClinicalTrials.gov

COVID-19 Registries for Hematologic Conditions

• ASH RC COVID-19 Registry for Hematology
  The ASH Research Collaborative’s (ASH RC) Data Hub is capturing data on people who test positive for COVID-19 and have been or are currently being treated for a hematologic condition. As data are received, near real-time observational data summaries are reported for clinicians on the front line of the COVID-19 pandemic. Clinicians and other health care providers worldwide are invited to enter de-identified data on all confirmed COVID-19 cases for hematology patients, regardless of recovery or active treatment status. Online data entry takes approximately 5 minutes to complete.
• Secure-SCD Registry (Medical College of Wisconsin)
  This registry is designed to capture pediatric and adult COVID-19 cases that are occurring across the world in patients living with sickle cell disease.
• CCC19 (COVID-19 and Cancer Consortium)
  A consortium of over 100 cancer centers and other organizations who have come together to collect data about cancer patients who have been infected with COVID-19.

Restarting Routine Clinical Practice

• AMA Physician Guide to Keeping Your Practice Open
• ASCO guide to cancer care delivery during COVID

Additional Resources

American Society of Hematology

• ASH Policy Resources
• ASH Summary of American Rescue Plan Act of 2021
• ASH Summary of the Coronavirus Aid, Relief and Economic Security (CARES) Act
• Latest COVID-19 Resources from ASH Publications
  • Blood: Latest COVID-19 Articles
  • Blood Advances: Latest COVID-19 Articles
    • A toolkit for the collection of thrombosis-related data elements in COVID-19 clinical studies
  • ASH Clinical News: COVID-19 News
  • The Hematologist: COVID-19 Articles and Podcasts 

Archived Webinars

• Webinar: Town Hall on NIH-organized Trials of Antithrombotic Agents in Patients with COVID-19: Hear the Latest and Become Involved in ACTIV-4
• Webinar: ASH Guidelines on Use of Anticoagulation in Patients with COVID-19
• Webinar: Sickle Cell Disease and COVID-19 Management in the Emergency Department

HHS (Department of Health and Human Services)

• COVID-19 and You: A Resource for Patients and Health Care Professionals

COVID-19: General Resources

Institute for Health Metrics and Evaluation

Johns Hopkins COVID tracker

AMA (American Medical Association)

CDC (Centers for Disease Control and Prevention)

• Updated: Infection Control Guidance
• Strategies to extend use of PPE

WHO (World Health Organization)

Subspecialty Societies

AABB (American Association of Blood Banks)

• AABB convalescent plasma donation locations

ACP (American College of Physicians)

ASCO (American Society of Clinical Oncology)  

• Road to recovery report: Lessons learned from COVID-19

ASTCT (American Society for Transplantation and Cellular Therapy)

• Interim Guidelines for COVID-19 Management

EBMT (European Society for Blood Marrow Transplantation)

EHA (European Hematology Association)

• Recommendations for hematologists in COVID-19 crisis

IDSA (Infectious Diseases Society of America)

• COVID-19 Resource Center

ISTH (International Society of Thrombosis and Hemostasis)

NCCN (National Comprehensive Cancer Network)

Journals

New England Journal of Medicine

• Coronavirus (Covid-19): Articles and other resources

JAMA (Journal of the American Medical Association)

• JAMA Network COVID-19 collection

The Lancet

• COVID-19 Resource Centre

Journal of Thrombosis and Haemostasis

• COVID-19 in Journal of Thrombosis and Haemostasis 

UpToDate

• Coronavirus disease 2019 (COVID-19)

British Journal of Haematology

• COVID-19 and Haematology

Additional Resources

• Coronavirus Tech Handbook (manual for front-line providers)

Resources for Researchers

American Society of Hematology

• ASH COVID-19 Research Agenda for Hematology
• Summary of NIH Guidance on Grants, Operations During COVID-19 Response

FDA (Food and Drug Administration)

• FDA statistical considerations for clinical trials during COVID
• FDA Guidance on Clinical Trials
• FDA issues guidance on emergency INDs for convalescent plasma for COVID-19

NIH (National Institutes of Health)

• COVID-19 Seroprevalence Studies Hub
  CDC and NIH have developed the COVID-19 Seroprevalence Studies Hub to provide an interactive dashboard to compare COVID19 serology studies across the country. 
• Summary of NIH ACTIV trials: Accelerating COVID-19 therapeutic interventions and vaccines
• NOSI from NIAID for Limited Clinical Trials to Evaluate Therapeutic and Vaccine Candidates Against SARS-CoV02 – expires 9/1/2021
• COVID-19: Information for NIH Applicants and Recipients of NIH Funding

Other Resources

• LitCovid: a curated literature hub by NLM
  This hub tracks up-to-date scientific information about COVID-19. Articles are updated daily and are categorized by different research topics and geographic locations.
  
• Blood and Bone Seminar 
  Dr. Kellie Machlus from Harvard Medical School and Brigham and Women’s Hospital has organized this seminar series to continue scientific education during this time of travel restrictions and meeting cancellations.
• Connecting the Scientific Community Seminar Series 
  Drs. Kornelia Polyak and David Weinstock from Dana-Farber/Harvard Cancer Center have organized this seminar series (12:00 pm Eastern every Tuesday and Thursday) to facilitate scientific exchanges during the COVID-19 restrictions.

Resources for Trainees

Frequently Asked Questions

• COVID-19 and Trainees: General Information (Version 1.1; last updated October 6, 2020)
• COVID-19 and Fellows (Version 1.1; last updated October 6, 2020)
• COVID-19 and Postdoctorate Students (Version 1.1; last updated October 6, 2020)
• COVID-19 and Residents (Version 1.1; last updated October 6, 2020)