David T. Teachey, MD, Children’s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA
Using the Genetics of the Autoimmune Lymphoproliferative Syndrome to Guide Therapy

Ronald W. Stam, PhD, Erasmus Medical Center - Sophia's Children's Hospital, Rotterdam, Netherlands
Mixed Lineage Leukemia Gene Rearrangements - Epigenetic Diseases Require Epigenetic Treatments

David Lillicrap, MD Queen's University, Kingston, ON, Canada
Genetic Characterization of Hemophilia and Implications for Novel Therapies

Nir Barzilai, MD, Albert Einstein College of Medicine, New York, NY
Genetics and Epigenetics of Aging

Rafael de Cabo, PhD, National Institute on Aging, National Institutes of Health, Baltimore, MD
Calorie Restriction and Aging

David Sinclair, PhD, Harvard Medical School, Boston, MA
Does Declining Mitochondrial NAD+ and Unscheduled Opening of Mitochondrial Transition Pore Promote Mammalian Aging?

Nicole Soranzo, PhD, Wellcome Trust Sanger Institute, Hinxton, United Kingdom
Genome-Wide Analysis Identifies Regulators of Hematologic Parameters

Mary V. Relling, PharmD, St. Jude Children’s Research Hospital, Memphis, TN
Genomic Variants Associated With Childhood Acute Lymphoblastic Leukemia

Steven McCarroll, PhD, Massachusetts General Hospital, Boston, MA
Genome Variation and Donor-Recipient Compatibility in Graft-Versus-Host Disease

Timm Schroeder, PhD, Institute of Stem Cell Research, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Munich/Neuherberg, Germany
Cytokines Instruct Hematopoietic Lineage Choice

Pier Paolo Pandolfi, MD, PhD, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
Role of Pokemon/LRF in Lineage Fate Decisions

Michael H. Sieweke, PhD, Centre d’Immunologie de Marseille Luminy (CIML), Marseille, France
MafB Restricts M-CSF-Instructed Lineage Choice in HSC

Eric D. Green, MD, PhD, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD
Genomics in 2K10: Fulfilling the Promise of a Sequenced Human Genome

Stuart H. Orkin, MD, Children’s Hospital, Dana-Farber Cancer Institute, Boston, MA
New Strategies to Define Regulators of Fetal Hemoglobin

David Ginsburg, MD, Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI
The COPII Pathway and Hematologic Disease

Thomas Renné, MD, PhD, Karolinska Institute, Stockholm, Sweden
In Vivo Roles for Factor XII

David Gailani, MD, Vanderbilt University School of Medicine, Nashville, TN
New Insights Into Factor XI Function: From Biochemistry to Animal Models

Uri Seligsohn, MD, Sheba Medical Center, Tel Aviv University, Ramat Gan, Israel
Factor XI in Clinical Bleeding and Thrombotic Disorders

Laurie H. Glimcher, MD, Harvard Medical School and Harvard School of Public Health, Boston, MA
Genetic Control of Th1/Th2 Cell Fate

Wayne W. Hancock, MD, PhD, The Children’s Hospital of Philadelphia, Philadelphia, PA
Epigenetic Regulation of Regulatory T-Cells: Impact on Autoimmunity and Graft Rejection

Pavan Reddy, MD, University of Michigan, Ann Arbor, MI
Translating Epigenetic Alterations Into Improvements in Patient Care

Gregory M. Vercellotti, MD, University of Minnesota, Minneapolis, MN
Heme and the Vasculature: How the Endothelium Protects Itself Against Toxic Iron

Karl A. Nath, MBChB, Mayo Clinic College of Medicine, Rochester, MN
Iron Toxicity in the Kidney and Pancreas

Tracey Rouault, MD, National Institute of Child Health and Development, National Institutes of Health, Bethesda, MD
Brain Iron Metabolism and Toxicity

Stephen B. Baylin, MD, The Johns Hopkins University, Baltimore, MD
The Epigenetic Regulation of Gene Expression

Kapil N. Bhalla, MD, Medical College of Georgia, Augusta, GA
Epigenetic Dysregulation in Lymphoid Malignancies

Susan Bates, MD, National Cancer Institute, National Institutes of Health, Bethesda, MD
Epigenetic Modulation and Therapy of Lymphoid Malignancies

Dinesh S. Rao, MD, PhD, University of California – Los Angeles, Los Angeles, CA
MicroRNA Regulators of Immune Cell Function

Curt I. Civin, MD, University of Maryland School of Medicine, Baltimore, MD
MicroRNA Maestros of Hematopoiesis

Judy Lieberman, MD, PhD, Immune Disease Institute, Harvard Medical School, Boston, MA
Targeting MicroRNA for Cancer Therapy

William Vainchenker, MD, PhD, Institut Gustave Roussy, Villejuif, France
Novel Mutations: Dissecting Pathogenetic Contribution

Richard A. Van Etten, MD, PhD, Tufts Medical Center, Lexington, MA
Mouse Models of Myeloproliferative Disease and Their Use in Preclinical Drug Testing

Ayalew Tefferi, MD, Mayo Clinic Graduate School of Medicine, Rochester, MN
JAK2 Inhibitor Therapy and Mechanisms of Response

William Matsui, MD, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD
Origin of the Myeloma Stem Cell

Alberto Orfao, MD, PhD, Universidad de Salamanca, Salamanca, Spain
Immunophenotypic Analysis of Myeloma Precursors: Antigens for Therapeutic Targeting

Constantine S. Mitsiades, MD, PhD, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
How to Overcome Myeloma Stem Cell Resistance to Therapy - Targeting the Stem Cell Niche

Willem Hendrik Ouwehand, MD, PhD, University of Cambridge, Cambridge, United Kingdom
Functional Genomics Approaches to Platelet Signaling

Scott L. Diamond, PhD, University of Pennsylvania, Philadelphia, PA
Systems Biology to Predict Platelet Function

Paul F. Bray, MD, Jefferson Medical College, Philadelphia, PA
MicroRNA in Platelet Production and Activation

Hanna Mikkola, MD, PhD, Broad Stem Cell Research Center at University of California – Los Angeles, Los Angeles, CA
Origin of Hematopoietic Stem Cells

Douglas J. Hilton, PhD, Walter and Eliza Hall Institute, Parkville, Victoria, Australia
Regulating Lineage Commitment in Adult Hematopoietic Stem Cells

Norman N. Iscove, MD, PhD, The Ontario Cancer Institute, University Health Network, Toronto, ON, Canada
Stability of Self-Renewal in Hematopoietic Stem Cells

Didier Stainier, PhD, University of California – San Francisco, San Francisco, CA
Angioblast Behavior in Arterial-Venous Segregation

Nancy A. Speck, PhD, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA
Hemogenic Endothelium

Shahin Rafii, MD, Howard Hughes Medical Institute and Genetic Medicine, Weill Cornell Medical College, New York, NY
Hematopoietic Support by Endothelium

Anna Rita Migliaccio, PhD, Mount Sinai School of Medicine, New York, NY
Expansion of Red Blood Cells for Transfusion

Mortimer Poncz, MD, The Children’s Hospital of Philadelphia, Philadelphia, PA
Expansion of Platelets for Transfusion

Helen E. Heslop, MD, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX
Expansion of Lymphocytes for Cell-Based Therapeutics

Nicholas P. Restifo, MD, National Cancer Institute, National Institutes of Health, Bethesda, MD
Improving Adoptive Immunotherapy Using Less-Differentiated T cells

Catherine M. Bollard, MBChB, MD, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX
Anti-Viral Cytotoxic T-Lymphocyte Therapy

Cameron J. Turtle, MBBS, PhD, Fred Hutchinson Cancer Research Center, Seattle, WA
Chemotherapy-Resistant T Cells