- Circulating Tumor DNA in Lymphoma Monitoring: Fantasy, Fad, or Fact?September 04, 2018 | Annette S. Kim, MD, PhD
Dr. Kim discusses a study that showcases the utility of circulating tumor DNA monitoring in classic Hodgkin lymphoma.
- Not All Large Cells Are Created Equal: Is Genomic Classification the New Frontier in Diffuse Large B-cell Lymphoma?August 29, 2018 | Costas K. Yannakou, MBBS (Hons), FRACP, FRCPA | Andrew Roberts, MBBS, PhD, FRACP, FRCPA
Dr. Roberts and Dr. Yannakou discuss a study that explores the genomic landscape of diffuse large B-cell lymphoma and maps specific combinations of genetic changes onto cell-of-origin categories defined by gene-expression profiling.
- Refining and Redefining the Heterogeneity of DLBCLAugust 29, 2018 | Caron A. Jacobson, MD
Dr. Jacobson reviews a study that led to the refinement of our current understanding of the genetic and molecular subtypes of diffuse large B-cell lymphoma and has implications for the design of new related treatment trials.
- Redefining Risks in Multiple Myeloma is Still a Work in ProgressAugust 27, 2018 | Tarek H. Mouhieddine, MD | Irene M. Ghobrial, MD
Dr. Mouhieddine and Dr. Ghobrial discuss the importance of redefining risk-stratification in multiple myeloma.
- JAK1/2 Inhibitors Linked to Aggressive B-cell Lymphoma Risk in Myelofibrosis and Pre-existing B-cell Clones May Mark Those at RiskAugust 24, 2018 | Sioban Keel, MD
Dr. Keel looks at whether JAK1/2 inhibitor therapy in patients with myeloproliferative neoplasms alters the risk of lymphoma development.
- Shedding Light on Migration of the Hematopoietic Niche Into BoneAugust 24, 2018 | Paul Moss, PhD
Dr. Moss reviews a study that looks at selective forces that drive the migration of the hematopoietic niche into bone.
- Do Plasma Levels of Direct Oral Anticoagulants Correlate With Hemorrhagic and Thrombotic Complications?August 21, 2018 | Stephan Moll, MD
Dr. Moll discusses a study that looks at whether plasma levels of direct oral anticoagulants correlate with hemorrhagic and thrombotic complications.
- Microbial Signals May Drive Leukemia Development in Subjects With Clonal HematopoiesisAugust 20, 2018 | Omar Abdel-Wahab, MD
Dr. Abdel-Wahab reviews a study that suggests dissemination of bacteria from the gastrointestinal system and ensuing microbial-dependent inflammation may drive the development of myeloid malignancy in subjects with clonal hematopoiesis.
- Venous Thrombosis on One Side and Bleeding on the Other: How to Walk the Fence in Cancer Patients With Thrombosis and ThrombocytopeniaAugust 15, 2018 | Lori-Ann Linkins, MD, MSc(Clin Epi), FRCPC
Dr. Linkins provides guidance on how to manage recurrent thrombosis and bleeding in a cancer patient with severe thrombocytopenia that develops VTE.