- Voxelotor: Changing the Disease by Changing the ConformationOctober 23, 2019 | November-December 2019, Volume 16, Issue 6
Drs. Wilson, Monahan, Little, and Osunkwo discuss a trial that tests voxelotor, a new disease-modifying therapy being considered for sickle cell disease.
- To Breathe or Not to Breathe... Does It Matter for SCD VOC?August 06, 2019 | September-October 2019, Volume 16, Issue 5
Dr. Osunkwo reviews a study that will explore the impact of continuous positive airway pressure on improving rates of vaso-occlusive crisis as well as several biologic parameters of disease severity in individuals with SCD and comorbid obstructive sleep apnea.
- Poorer Pain Control With Normal Saline Bolus in Children With Sickle Cell Acute Vaso-Occlusive PainJune 18, 2019 | July-August 2019, Volume 16, Issue 4
Dr. Osunkwo reviews a study that challenges the belief that normal saline boluses are the best option to treat acute vaso-occlusive pain in sickle cell disease.
- Could Lullabies and Bedtime Stories Help Youth With SCD Have Less Pain?April 15, 2019 | May-June 2019, Volume 16, Issue 3
Dr. Osunkwo explores the bidirectional relationship between age, sleep, and pain in youth with sickle cell disease.
- Hydroxyurea for Children With Sickle Cell Anemia in Sub-Saharan Africa: The Child That Comes and Goes Away Can Come to Stay With HydroxyureaFebruary 07, 2019 | March-April 2019, Volume 16, Issue 2
Dr. Osunkwo discusses the REACH Trial, which demonstrates the safety and efficacy of hydroxyurea use among children in four sub-Saharan African countries, and its implications for treating sickle cell disease.