Dr. Ernest Beutler was honored with the Wallace H. Coulter Award for Lifetime Achievement in Hematology at the 2007 American Society of Hematology Annual Meeting. He was a physician-scientist whose career has spanned more than half a century. This is his acceptance speech.

Among his many accomplishments, Dr. Beutler made significant contributions to the understanding of the biochemical and genetic causes underlying disorders of the red blood cell, originated the concept of X-chromosome inactivation in human females independently of mouse geneticist Mary Lyon, and provided the first formal proof of this phenomenon, an insight that has become one of the cornerstones of mammalian genetics. He also developed screening tests for the genetic disorders galactosemia and Gaucher disease.

Learn more about the life of Dr. Beutler by visiting his Legends in Hematology profile.

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