Below you will find a collection of articles from Hematology, the ASH Education Program, written by experts in pediatric hematology and oncology, including articles on pediatric leukemia and lymphoma, and sickle cell disease. Additional links to organizations focusing on pediatric issues are also available.

Cancers

Leukemias (acute)

• Late Effects of Acute Lymphoblastic Leukemia Therapy in Patients Diagnosed at 0-20 Years of Age (2011) 
• Pediatric Acute Leukemia Therapies Informed by Molecular Analysis of High-Risk Disease (2011) 
• Recommendations for Broader Coverage Antifungal Prophylaxis in Childhood Acute Myeloid Leukemia: ASH Evidence-Based Review 2011 (2011) 
• Targeting Epigenetic Programs in MLL-Rearranged Leukemias (2011) 
• Tyrosine Kinase Inhibitor Use in Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia (2011) 
• Pediatric Acute Lymphoblastic Leukemia: Is There Still a Role for Transplant? (2010) 
• Treatment of Acute Lymphoblastic Leukemia in Children and Adolescents: Peaks and Pitfalls (2008) 
• Tumor-Specific Genetic Lesions and Their Influence on Therapy in Pediatric Acute Lymphoblastic Leukemia (2006) 

Leukemias (chronic)

• Treatment of Pediatric Chronic Myeloid Leukemia in the Year 2010: Use of Tyrosine Kinase Inhibitors and Stem-Cell Transplantation (2010)  

Lymphomas

• Burkitt Lymphoma: Revisiting the Pathogenesis of a Virus-Associated Malignancy (2007)  
• Diagnosis and Treatment of Childhood Non-Hodgkin Lymphoma (2007) 
• Should Adolescents with NHL Be Treated as Old Children or Young Adults? (2007) 

Myelodysplastic Syndromes

• Childhood Myelodysplastic Syndrome: Focus on the Approach to Diagnosis and Treatment of Juvenile Myelomonocytic Leukemia (2010)  

Benign Diseases

Cytopenias

• Classification of Childhood Aplastic Anemia and Myelodysplastic Syndrome (2011) 
• Clinical Approach to Marrow Failure (2009) 
• Congenital Neutropenia (2009) 
• Disorders of Neutrophil Number and Function (2006)  
• Hereditary Periodic Fever Syndromes (2005) 

Hemoglobinopathies

• Hematopoietic Stem Cell Transplantation for Sickle Cell Disease: Current Practice and Emerging Trends (2011) 
• Primary Prophylaxis in Sickle Cell Disease: Is It Feasible? Is It Effective? (2011)  
• Pulmonary Hypertension, Tricuspid Regurgitant Velocity Screening, and the Nitric Oxide Pathway (2011)  
• Secondary Prevention of Overt Strokes in Sickle Cell Disease: Therapeutic Strategies and Efficacy (2011) 
• What Is the Evidence for Using Hydroxyurea for Secondary Stroke Prevention? (2011) 
• Newborn Screening for Non-Sickling Hemoglobinopathies (2009)  
• Current and Future Therapies of Sickle Cell Anemia: An Historical Perspective (2008)  
• Novel Small Molecule Therapeutics for Sickle Cell Disease: Nitric Oxide, Carbon Monoxide, Nitrite, and Apolipoprotein A-I (2008)  
• Gene Replacement Therapy for Sickle Cell Disease and Other Blood Disorders (2008)  
• Pain Management in Sickle Cell Disease: Palliative Care Begins at Birth? (2008)  
• Mechanisms of Vasculopathy in Sickle Cell Disease and Thalassemia (2008)  

Hemostasis/Thrombosis

• Bleeding and Clotting Disorders in Pediatric Liver Disease (2011) 
• Heparin-Induced Thrombocytopenia Screening and Management in Pediatric Patients (2011) 
• New Anticoagulants in Children (2008) 
• Pediatric Thrombophilia and Thrombosis: An Historical Perspective (2008) 
• Thrombophilia in Children: Who to Test, How, When, and Why? (2008) 
• Thrombophilia States and Markers of Coagulation Activiation in the Prediction of Pediatric Venous Thromboembolic Outcomes: A Comparative Analysis with Respect to Adult Evidence (2008) 

Immune Deficiency

• New Insights Into the Biology of Wiskott-Aldrich Syndrome (WAS) (2009)  
• Primary Immunodeficiencies (PIDs) Presenting With Cytopenias (2009)  
• Chronic Granulomatous Disease and Other Disorders of Phagocyte Function (2005) 
   

Stem Cell Transplantation

• Stem Cell Transplantation in Inherited Metabolic Disorders (2011) 

Other

• Approach to Hemophagocytic Syndromes 

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