Below you will find a collection of articles from Hematology, the ASH Education Program, written by experts in the field about current treatments for myeloproliferative neoplasms (MPN), including essential thrombocythemia, myelofibrosis, and polycythemia. This Web site also provides a link to an organization that informs and supports MPN patients and their families.

Biology/Pathogenesis

• The JAK2V617F Mutation in Polycythemia Vera and Other Myeloproliferative Disorders: One Mutation for Three Diseases? (2008) 
• Navigating the Evolving Paradigms in the Diagnosis and Treatment of Myeloproliferative Disorders (2007) 
• The Genetic Basis of Myeloproliferative Disorders (2007) 

Myeloproliferative

• Genetic and Epigenetic Complexity in Myeloproliferative Neoplasms (2011)  
• Myelodysplastic/Myeloproliferative Neoplasms (2011) 
• Therapeutic Potential of JAK2 Inhibitors (2009) 
• Philadelphia Chromosome-Negative Myeloproliferative Disorders: An Historical Perspective (2008) 
• From Palliation to Epigenetic Therapy in Myelofibrosis (2008) 

Essential Thrombocytosis/Thrombocythemia (High Platelet Count)

• Management of Essential Thrombocythemia (2011) 
• Rethinking Disease Definitions and Therapeutic Strategies in Essential Thrombocythemia and Polycythemia Vera (2010) 
• Pathogenesis and Management of Essential Thrombocythemia (2009) 
• Thrombocytosis (2009) 
• New Advances in the Pathogenesis and Therapy of Essential Thrombocythemia (2008) 

Myelofibrosis

• Management of Myelofibrosis (2011)  
• Assessing New Therapies and Their Overall Impact in Myelofibrosis (2010) 
• From Palliation to Epigenetic Therapy in Myelofibrosis (2008) 

Other

• Eosinophilic Myeloproliferative Disorders (2011) 
• Myeloproliferative Disease in Pregnancy and Other Management Issues (2006) 

Pathophysiology / Diagnostics

• World Health Organization Classification, Evaluation, and Genetics of the Myeloproliferative Neoplasm Variants (2011) 
• Navigating the Evolving Paradigms in the Diagnosis and Treatment of Myeloproliferative Disorders (2007) 
• The Genetic Basis of Myeloproliferative Disorders (2007) 

Polycythemia (High Red Blood Cell Count)

• Idiopathic Erythrocytosis: A Disappearing Entity (2009) 

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