Below you will find a collection of articles from Hematology, the ASH Education Program, written by experts in the field about current treatments for acute leukemia. To learn more about leukemia, please see our general information page about the disease. A number of links to organizations that inform and support patients with leukemia and their families are also available.

General

• Angiogenesis: A Target in Solid Tumors, Also in Leukemia? (2011) 
• Targeting Epigenetic Programs in MLL-Rearranged Leukemias (2011) 
• Darwin and Evolutionary Tales in Leukemia (2009) 
• Management of Thrombohemorrhagic Syndromes (THS) in Hematologic Malignancies (2007) 
• Double Hazard of Thrombophilia and Bleeding in Leukemia (2007) 

Acute Lymphoblastic (Lymphocytic) Leukemia (ALL)

• Current Treatment of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia (2011) 
• Late Effects of Acute Lymphoblastic Leukemia Therapy in Patients Diagnosed at 0-20 Years of Age (2011) 
• Novel Antibody-Based Therapies For Acute Lymphoblastic Leukemia (2011) 
• Tyrosine Kinase Inhibitor Use in Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia (2011) 
• Minimal Residual Disease in Acute Lymphoblastic Leukemia (2010) 
• Treating the “Older” Adult With Acute Lymphoblastic Leukemia (2010) 
• Adolescents and Young Adults with Acute Lymphoblastic Leukemia (2010) 
• The Role of NOTCH1 Signaling in T-ALL (2009) 
• Transplantation in Adult ALL (2009) 
• Evolving Paradigms in the Therapy of Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in Adults (2009) 
• Acute Lymphoblastic Leukemia: An Historical Perspective (2008) 
• Molecular Determinants of Treatment Response in Acute Lymphoblastic Leukemia (2008) 
• Treatment of Acute Lymphoblastic Leukemia in Children and Adolescents: Peaks and Pitfalls (2008) 
• Myths and Lessons from the Adult/Pediatric Interface in Acute Lymphoblastic Leukemia (2006) 
• Central Nervous System Disease in Acute Lymphoblastic Leukemia: Prophylaxis and Treatment (2006) 

Acute Myeloid Leukemia (AML)

• Genomics of AML: Clinical Applications of Next-Generation Sequencing (2011) 
• Impact of Genetic Features on Treatment Decisions in AML (2011) 
• Novel Approaches to the Treatment of Acute Myeloid Leukemia (2011) 
• High Cytogenetic or Molecular Genetic Risk Acute Myeloid Leukemia (2010) 
• New Prognostic Markers in Acute Myeloid Leukemia: Perspective from the Clinic (2010) 
• New Trends in the Standard of Care for Initial Therapy of Acute Myeloid Leukemia (2010) 
• Treating the Elderly Patient with Acute Myelogenous Leukemia (2010) 
• Independent Prognostic Factors for AML Outcome (2009) 
• Optimal Induction and Post-Remission Therapy for AML in First Remission (2009) 
• What Is the Role of Reduced-Intensity Transplantation in the Treatment of Older Patients With AML? (2009) 
• ASH Evidence-Based Guidelines: Is There a Role for Second Allogeneic Transplant After Relapse? (2009) 
• Acute Myeloid Leukemia: The Challenge of Capturing Disease Variety (2008) 
• Acute Myeloid Leukemia; Decided Victories, Disappointments, and Detente: An Historical Perspective (2008) 
• Curative Strategies in Acute Promyelocytic Leukemia (2008) 
• Molecular Genetic Pathways as Therapeutic Targets in Acute Myeloid Leukemia (2008) 
• Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia When a Matched Related Donor Is Not Available (2008) 

Acute Promyelocytic (Progranulocytic) Leukemia (APL)

• Treatment of Acute Promyelocytic Leukemia (2006) 
• The Biology of Acute Promyelocytic Leukemia and Its Impact on Diagnosis and Treatment (2006) 
• Management of APL in Developing Countries: Epidemiology, Challenges and Opportunities for International Collaboration (2006) 

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