Below you will find a collection of articles from Hematology, the ASH Education Program, written by experts in the field about current treatments for various types of anemia. To learn about the disorder’s symptoms and causes, please see our general information page on anemia, as well as our page about anemia in older adults and in pregnant women. A number of links to organizations that inform and support anemia patients and their families are also available. Additional information about a specific type of anemia, sickle cell disease, can also be found on this website.

Aplastic Anemia

• Clonal Evolution in Aplastic Anemia (2011) 
• Diagnosis and Management of Aplastic Anemia (2011) 
• Management of Paroxysmal Nocturnal Hemoglobinuria in the Era of Complement Inhibitory Therapy (2011) 
• Therapy for Aplastic Anemia (2011)  
• Aplastic Anemia: First-line Treatment by Immunosuppresion and Sibling Marrow Transplantation (2010) 
• Alternative Donor Transplantation for Aplastic Anemia (2010) 

General Information

• Anemia in Elderly Patients: An Emerging Problem for the 21^st Century (2010) 
• Anemia of Inflammation (2010) 
• Parenteral Iron Therapy in Cancer-Associated Anemia (2010) 
• Hematologic Disorders after Solid Organ Transplantation (2010) 

Hemolytic Anemia

• Atypical Hemolytic Uremic Syndrome, Genetic Basis, and Clinical Manifestations (2011) 
• Too Much of a Good Thing at the Site of Tissue Injury: The Instructive Example of the Complement System Predisposing to Thrombotic Microangiopathy (2011) 
• Drug-Induced Immune Hemolytic Anemia (2009) 
• Immune Hemolytic Anemia - Selected Topics (2009) 
• Malaria, Erythrocytic Infection, and Anemia (2009) 
• Thrombotic Thrombocytopenic Purpura: A Moving Target (2006) 
• Red Cell Membrane Disorders - Hereditary Spherocytosis and Elliptocytosis (2005) 
• Red Cell Enzymes - Pyruvate Kinase Deficiency, G6PD Deficiency, etc. (2005) 

Hemoglobinopathies

Sickle Cell Disease

• Primary Prophylaxis in Sickle Cell Disease: Is It Feasible? Is It Effective? (2011) 
• Pulmonary Hypertension, Tricuspid Regurgitant Velocity Screening, and the Nitric Oxide Pathway (2011) 
• Secondary Prevention of Overt Strokes in Sickle Cell Disease: Therapeutic Strategies and Efficacy (2011) 
• Neurobiological Mechanisms of Pain in Sickle Cell Disease (2010) 
• Sickle-Cell Pain: Advances in Epidemiology and Etiology (2010) 
• Evidence-Based Mini-Review: Are Systemic Corticosteroids an Effective Treatment for Acute Pain in Sickle Cell Disease? (2010) 
• Sickle-Cell Trait: Novel Clinical Significance (2010) 
• Asthma and Sickle Cell Disease: Two Distinct Diseases or Part of the Same Process? (2009) 
• Novel Therapies in Sickle Cell Disease (2009) 
• Hematopoietic Stem Cell Gene Transfer for the Treatment of Hemoglobin Disorders (2009) 
• Advances in the Use of Hydroxyurea (2009) 
• Current and Future Therapies of Sickle Cell Anemia: An Historical Perspective (2008) 
• Pain Management in Sickle Cell disease: Palliative Care Begins at Birth? (2008) 
• Mechanisms of Vasculopathy in Sickle Cell Disease and Thalassemia (2008) 
• Novel Small Molecule Therapeutics for Sickle Cell Disease: Nitric Oxide, Carbon Monoxide, Nitrite, and Apolipoprotein A-I (2008) 
• Gene Replacement Therapy for Sickle Cell Disease and Other Blood Disorders (2008) 
• Role of Adhesion Molecules and Vascular Endothelium in the Pathogenesis of Sickle Cell Disease (2007) 
• Hypercoagulability in Sickle Cell Disease: New Approaches to an Old Problem (2007) 
• Coagulation in the Pathophysiology of Hemolytic Anemias (2007) 
• Red Cell Exchange in Sickle Cell Disease (2006) 
• Prevention and Management of Stroke in Sickle Cell Anemia (2006) 

Thalassemia

• Real-World Use of Iron Chelators (2011) 
• Targeted Therapeutic Strategies for Fetal Hemoglobin Induction (2011) 
• Genetic Therapy for Beta-Thalassemia: From the Bench to the Bedside (2010) 
• Update on Iron Chelators in Thalassemia (2010) 
• Hematopoietic Stem Cell Transplantation in Thalassemia (2010) 
• Newborn Screening for Non-Sickling Hemoglobinopathies (2009) 
• Hematopoietic Stem Cell Gene Transfer for the Treatment of Hemoglobin Disorders (2009) 
• Alpha Thalassemia Major - New Mutations, Intrauterine Management, and Outcomes (2009) 
• Hb H Disease: Clinical Course and Disease Modifiers (2009) 
• Newborn Screening for Non-Sickling Hemoglobinopathies (2009) 
• Coagulation in the Pathophysiology of Hemolytic Anemias (2007) 

Hemoglobin E

• Newborn Screening for Non-Sickling Hemoglobinopathies (2009) 
• Hemoglobin E Syndromes (2007) 
• Reduced-Intensity Regimens in Allogeneic Hematopoietic Stem Cell Transplantation for Hemoglobinopathies (2006) 

Thrombocytopenia

• Coagulation in the Pathophysiology of Hemolytic Anemias (2007) 

Porphyrias

• Neurovisceral Porphyrias: What a Hematologist Needs to Know (2005) 

back to top