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  • Information on How the New ESA REMS Program Will Affect MDS Patients
  • March 11, 2010
  • On March 24, the Food and Drug Administration (FDA) will require that all drugs called erythropoiesis-stimulating agents (ESAs) be prescribed and used under a risk management program, known as a risk evaluation and mitigation strategy (REMS), to ensure the safe use of these drugs.

  • March is DVT Awareness Month
  • March 9, 2010
  • ASH continues to work with several advocacy coalitions and the Department of Health and Human Services on efforts to increase public awareness of DVT as a major public health problem.

  • Persons With Quebec Platelet Disorder Have a Tandem Duplication of PLAU
  • March 8, 2010
  • Quebec platelet disorder (QPD) is an autosomal dominant bleedingdisorder linked to a region on chromosome 10 that includes PLAU, the urokinase plasminogen activator gene. QPD increases urokinase plasminogen activator mRNA levels, particularly during megakaryocyte differentiation, without altering expression of flanking genes.

  • ASH Announces 2010 Scholar Award Winners
  • March 4, 2010
  • (WASHINGTON) – The American Society of Hematology (ASH) announces the 2010 recipients of its Scholar Awards. The program is designed to support hematologists who have chosen a career in research by providing partial salary or other support during that critical period required for completion of training and achievement of status as an independent investigator.

  • Medicare Physician Payment Cut Averted Through March 2010
  • March 2, 2010
  • The 21 percent Medicare physician payment cut that began March has been stopped. After much delay, the Senate passed legislation (HR 4691) that extends the CY 2009 Medicare physician payment level through the end of March. Senator Jim Bunning (R-KY), who had prevented passage of this measure, backed down late March 1, allowing passage of the legislation.

  • The Interconnectedness of Many Diseases Leads to the Bone Marrow...
  • March 1, 2010
  • There was a time when we thought we understood disease-damaged tissue. Take for example diabetic retinopathy, one of the most important causes of visual loss worldwide. In the case of non-proliferative diabetic retinopathy, we were taught that chronic hyperglycemia led to vascular changes resulting in retinal injury, ischemia, and acellular retinal capillaries.

  • Microvesicles in CLL: A New Form of Tumor and Stromal Cell Communication
  • March 1, 2010
  • Over the past decade a theme has emerged identifying the tumor microenvironment as something essential to preserving leukemia cell survival. This is particularly true in chronic lymphocytic leukemia (CLL), where spontaneous apoptosis of tumor cells occurs when the tumor cells are removed from the microenvironment.

  • Setting Sights on a Bad Actor
  • March 1, 2010
  • Myeloid cell leukemia-1(Mcl-1) protein is a member of the Bcl-2 family of apoptotic regulatory proteins that is dysregulated in a variety of hematopoietic malignancies, including multiple myeloma, non-Hodgkin lymphoma, and mantle cell lymphoma.

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