The American Society of Hematology (ASH) will be presenting the second Clinical Research Training Institute in Latin America (CRTI-LA) program on April 23 and 24, 2014 in Florianópolis, Brazil.
This program is intended for early to mid-career hematology faculty working in Latin American countries who are engaged in clinical research and training and wish to become more familiar with clinical trial design and execution with the goal of mentoring early-career trainees in clinical research.
The CRTI–LA program is made up of two days with didactic sessions in the morning and small group sessions in the afternoon. The purpose of the didactic sessions is to introduce the participants to the fundamentals of clinical trial design and topics include The Importance of Good Mentoring, Developing Clinical Research Questions, Biostatistics, Searching the Literature, Overview of Trial Designs and What is Needed to Start Clinical Research, and How to Write an Abstract and Manuscript for Publication. The small group breakouts will allow faculty and participants to interact and to evaluate proposals based on didactic discussions. This format will also promote peer-review among participants. The program also includes, one-on-one faculty and participant sessions, which will allow each individual’s unique questions and setting to be addressed.
The CRTI-LA program will be held the two days prior to the Highlight of ASH (HOA) in Latin America program on April 25-26, 2014. ASH assumes all participants in CRTI-LA will also participate in HOA.
||February 28, 2014
|Applicants Notified of their Acceptance
|CRTI in Latin America Course, Florianópolis, Brazil
||April 23 and 24, 2014
- Have a current faculty appointment in a division or department of hematology or oncology in Latin America.
- Be proficient in written and spoken English.
- Have a medical degree with a clinical practice in hematology or hematologic malignancies.
- A clinical practice exclusively in solid tumors is not appropriate.
- Research interests focused exclusively on laboratory based research are not appropriate.
Faculty members within 15 years from the first faculty appointment will be prioritized. There is no fee to apply to the program. It is expected that the selected participants will match ASH's investment in the program by securing funding for their travel and lodging for CRTI-LA.
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- Applications must be submitted electronically to firstname.lastname@example.org by 11:59 pm, US Eastern Time, February 28, 2014.
- Only electronic submissions will be accepted.
- Only ONE submission will be accepted. No updates, revisions, changes, or additions will be accepted or considered.
- The file should be named in the following format: CRTI-LA Lastname-Firstname 2014 Application.pdf.
- All applications MUST include the required documents listed below, in the order below, and be submitted as one PDF file to be accepted or considered.
- CRTI-LA Application form
ASH provides this form. Please answer all questions
- Applicant’s curriculum vitae (maximum 5 pages) that includes the applicant’s complete contact information, description of the applicant’s present faculty position (including title of the position and major responsibilities), prior training in clinical research (if any), publications, list of trainees the applicant has mentored and their current position (if any), and any other relevant information specific to the applicant’s career in clinical research.
- Applicant’s goals for attendance (maximum one page). The applicant should state how attendance at CRTI will enhance their career.
Pre-course work: Selected participants must develop a one paragraph background section and a research question for a proposed study.
An email from ASH will be sent to the applicant within one business day of receiving the application to confirm receipt. If an email is not received, the applicant should notify ASH staff immediately. Failure to notify ASH could result in the application not being reviewed.
Any submission that does not follow the application requirements, is not formatted correctly, is lacking information, has incorrect information, or is lacking required documents may be deemed ineligible and may not be reviewed by the study section. There will be no appeals or consideration for additional or further review once an application has been determined to be ineligible.
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All eligible applications will be reviewed by a study section. Up to 20 participants will be selected. The selection criteria include:
- Meet application eligibility requirements.
- Demonstrate the potential to develop and sustain an investigator-initiated clinical research career in hematology. This will be adjudicated based upon the CV and goals for attendance.
- Demonstrate past productivity in academic research. It is expected that selected applicants will have at least one peer reviewed publication.
- Possess the potential to influence mentees in hematology as judged by the CV.
- Those selected to attend the program will be responsible for pre-course work to be brought to the workshop. Each person must develop a one paragraph background section and a research question for a clinical research study.
- Those selected will be responsible to arrange and pay for their own flight and hotel accommodations.
- Selected participants must agree to attend both days of the program.
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Pre-course work: Selected participants must develop a one page background section and a research question for a proposed study.
||Breakfast and Introductions
The Importance of Good Mentorship
Joseph R. Mikhael, MD, FRCPC
Med Mayo Clinic In Arizona
Good mentoring is a critical component of optimizing early success as a clinical investigator. The speaker will explain the role of the mentor and provide some examples of excellent mentorship and examples of poor mentorship. He/she will discuss not only the optimal attributes of an excellent mentor but also include what the scholar can do to improve the mentor-mentee relationship.
The Clinical Research Question
Sonali Smith, MD
University of Chicago
Defining the question that will define your research project is the most important (and often most difficult) component of a research project. A carefully developed question will reduce the amount of work required to complete a project and will facilitate the analysis and publication of the results. A poorly defined question will often lead to a difficult study course, complex analysis, and a publication that lacks clarity, and therefore impact. This presentation will review some of the characteristics of a well designed research question.
Introduction to Biostatistics
Lillian Sung, MD, PhD
The Hospital for Sick Children
Statistical analyses can take many diverse forms, but there are underlying principles common to most of them. It is essential that clinicians entering the world of clinical research have a solid understanding of these statistical principles. They will prove useful whether designing research projects or reading the results of research done by others. This presentation will provide a review of several concepts: hypothesis tests, p-values, power, sample size, and regression analysis.
The purpose of the small groups is to review research questions and evaluate feasibility of each participant's proposal. Peer review by other members of the group will be highly encouraged. Each participant's proposal will receive approximately 30 minutes of discussion.
Small Group Faculty:
Linda J. Burns, MD, University of Minnesota, Minneapolis, MN
Mark A. Crowther, MD, St. Joseph's Hospital, Hamilton, ON
Ruben A. Mesa, MD Mayo Clinic In Arizona, Scottsdale, AZ
Sonali Smith, MD, University of Chicago, Chicago, IL
Wendy Stock, MD, University of Chicago, Chicago, IL
||One-on-one faculty and participant sessions
Searching the Literature
Mark A. Crowther, MD
St. Joseph's Hospital
All research projects begin with a thorough search of the literature. This talk will discuss general concepts behind how to conduct a literature search and describe different databases available for searching.
Overview of Trial Designs and What you Need to Start your Research
Wendy Stock, MD
University of Chicago
This research will describe the different types of trial designs including observational and experimental methods. More specifically, cross-sectional, case-control and cohort studies, as well as randomized controlled trials will be described along with their advantages and disadvantages. In addition, this session will consider what items need to be addressed before starting your research.
How to Write an Abstract and Manuscript for Publication
Ruben A. Mesa, MD
Mayo Clinic in Arizona
The preparation of an abstract for a manuscript publication is a very important step in the communication of a research study or report. An abstract is a complete and concise description of key methodological features of the study and important research findings. It provides the all-important first impression and identifies the potential value or relevance of the research approach. If the abstract is well written, clearly presenting the why and how you did what you did, and finishing with an explanation of how your results address the reason for doing the study in the first place, it will entice readers to obtain a copy of the full manuscript report, build on the findings, and cite your work. If it it poorly written, your research may be ignored or untapped. This presentation will address reasons for giving an effective research presentation and will apply to both oral and poster presentations.
Other International Programs
Learn more about ASH's international programs and initiatives.
Questions regarding the Clinical Research Training Institute in Latin America should be directed to the ASH Training Department at email@example.com.
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