The American Society of Hematology (ASH) will be presenting the Clinical Research Training Institute in Latin America (CRTI–LA) program from 9:00 am – 6:00 pm on April 24, 2013 in Santiago, Chile.
This pilot program is intended for early-to mid-level hematology faculty working in Latin American countries who are engaged in clinical research and training and wish to become more familiar withclinical trial design and execution toward a goal of mentoring future CRTI-LA early-career trainees in clinical research.
The CRTI–LA program is made up of four didactic sessions, specifically designed to introduce the participants to the fundamentals of clinical trial design, and small group breakouts where faculty and participants interact to evaluate proposals based on didactic discussions. Didactic lectures include Developing Clinical Research Questions, Study Feasibility Assessment, Biostatistics, and How to Write an Abstract and Manuscript for Publication.
CRTI-LA faculty will be recruited from leaders in the ASH Clinical Research Training Institute who are skilled in all aspects of clinical trial design.
The CRTI–LA program will be held the day prior to the Highlights of ASH (HOA) in Latin America program on April 25-26, 2013. ASH assumes all participants in CRTI–LA will also participate in HOA in Santiago.
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Timeline
| Application Due |
January 22, 2013 |
| Applicants Notified of their Acceptance |
February 11, 2013 |
| Confirmation of Acceptance Due from Applicants |
March 12, 2013 |
| CRTI in Latin America Course, Santiago, Chile |
April 24, 2013 |
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Eligibility
Applicants must:
- Have a current faculty appointment and be within 20 years from first faculty appointment in a division or department of hematology or oncology in Latin America.
- Be proficient in written and spoken English.
- Have a medical degree with a clinical practice in hematology or hematologic malignancies.
- A clinical practice exclusively in solid tumors is not appropriate.
- Research interests focused exclusively on laboratory based research are not appropriate.
There is no fee to apply to the program. It is expected that the selected participants will match ASH's investment in the program by securing funding for their travel and lodging for CRTI-LA.
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Application Requirements
- Applications must be submitted electronically to training@hematology.org by 11:59 pm, US Eastern Time, January 22, 2013.
- Only electronic submissions will be accepted.
- Only ONE submission will be accepted. No updates, revisions, changes, or additions will be accepted or considered.
- The file should be named in the following format: CRTI-LA Lastname-Firstname 2013 Application.pdf.
- All applications MUST include the required documents listed below, in the order below, and be submitted as one PDF file to be accepted or considered.
- CRTI-LA Application form
ASH provides this form. Please answer all questions
- Applicant’s curriculum vitae (maximum 5 pages) that includes the applicant’s complete contact information, description of the applicant’s present faculty position (including title of the position and major responsibilities), prior training in clinical research (if any), publications, list of trainees the applicant has mentored and their current position (if any), and any other relevant information specific to the applicant’s career in clinical research.
- Applicant’s career development plan (maximum 2 pages)must include:
- An overview of the applicant’s expected career path and career goals including mentorship of trainees, description of the applicant’s clinical research goals, and applicant’s goals for training mentees in clinical research.
- Explanation of track record of interest and success in academic hematology and clinical research.
- Reason for wanting to participate in CRTI-LA, and how participation in the program can benefit applicant’s institution and future mentees.
- Institutional support letter (maximum 2 pages) written by the head of the division or department chair. The letter should describe the applicant’s abilities with respect to the environment and resources available to the applicant to conduct clinical research and be a mentor. The letter should also include a commitment to providing the applicant time to attend the Workshop.
Pre-course work: Selected participants must develop a one paragraph background section and a research question for a proposed study. Participants should also bring one research article (not a review) that relates to the proposed research question.
An email from ASH will be sent to the applicant within one business day of receiving the application to confirm receipt. If an email is not received, the applicant should notify ASH staff immediately. Failure to notify ASH could result in the application not being reviewed.
Any submission that does not follow the application requirements, is not formatted correctly, is lacking information, has incorrect information, or is lacking required documents may be deemed ineligible and may not be reviewed by the study section. There will be no appeals or consideration for additional or further review once an application has been determined to be ineligible.
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Selection Criteria
All eligible applications will be reviewed by a study section. Up to 20 participants will be selected. The selection criteria include:
- Meet application eligibility requirements.
- Demonstrate the potential to develop and sustain an investigator-initiated clinical research career in hematology. This will be adjudicated based upon the biosketch/CV, career development plan, and institutional letter of support.
- Demonstrate past productivity in academic research. It is expected that selected applicants will have at least one peer reviewed publication.
- Work in an environment that fosters academic productivity in clinical research and mentorship of future researcher. This will be judged by the institutional support letter.
- Possess the potential to influence mentees in hematology as judged by the biosketch/CV and career development plan.
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Award Terms
- Those selected to attend the program will be responsible for pre-course work to be brought to the workshop. Each person must develop a one paragraph background section and a research question for a clinical research study. Participants should also bring one research article (not a review) that relates to the proposed research question.
- Those selected will be responsible to arrange and pay for their own flight and hotel accommodations.
- Selected participants must agree to attend the dinner on the evening of April 23 and to attend the full day (9:00 am to 5:00 pm) of the program, including meals and breaks, on April 24.
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Curriculum
Pre-course work: Selected participants must develop a one page background section and a research question for a proposed study. Participants should also bring one research article (not a review) that relates to the proposed research question.
April 23
| 7:30 p.m. |
Dinner with faculty and participants – Dinner talk: Mentorship and Relationship Building. |
April 24
| 9:00 a.m. |
Developing Clinical Research Questions Developing the question that will define your research project is the most important (and often most difficult) component of a research project. A carefully developed question will reduce the amount of work required to complete a project and will facilitate the analysis and publication of the results. A poorly defined question will often lead to a difficult study course, complex analysis, and a publication that lacks clarity, and therefore impact. This presentation will review some of the characteristics of a well designed research question. |
10:00 a.m.
|
Break |
| 10:15 a.m. |
Study Feasibility Assessment This session will allow participants to assess the design, key drivers, biostatistical support, and environment feasibility of a trial to determine the viability of a project against factors such as investigator interest, cost, time, and resources as well as availability of target population, local medical practices, and competing trials. It is important to identify the potential risks and possible solutions before embarking on your project. This talk will also cover how to conduct pilot and feasibility studies, in the context of overall designs/phases of clinical research and trials.
|
| 11:15 a.m. |
Break |
| 11:30 a.m. |
Introduction to Biostatistics Statistical analyses can take many diverse forms, but there are underlying principles common to most of them. It is essential that clinicians entering the world of clinical research have a solid understanding of these statistical principles. They will prove useful whether designing research projects or reading the results of research done by others. This presentation will provide a review of several concepts: hypothesis tests, p-values, power, sample size, and regression analysis. |
| 12:30 pm |
Lunch |
| 1:30 p.m. |
Small Groups The small groups will review research questions and evaluate the feasibility of each trainee’s proposal. Peer review by other members of the group will be highly encouraged. Each trainee’s proposal will receive approximately 30 minutes of discussion. |
| 2:30 p.m. |
Break |
| 2:45 p.m. |
Small Groups Return to Small Groups |
| 3:45 p.m. |
Break |
| 4:00 p.m |
Small Groups Return to Small Groups |
| 5:00 p.m. |
How to Write an Abstract and Manuscript for Publication The preparation of an abstract for a manuscript publication is a very important step in the communication of a research study or report. An abstract is a complete and concise description of key methodological features of the study and important research findings. It provides the all-important first impression and identifies the potential value or relevance of the research approach. If the abstract is well written, clearly presenting the why and how you did what you did, and finishing with an explanation of how your results address the reason for doing the study in the first place, it will entice readers to obtain a copy of the full manuscript report, build on the findings, and cite your work. If it is poorly written, your research may be ignored or untapped. This presentation will address reasons for giving an effective research presentation and will apply to both oral and poster presentations. |
| 5:30 pm |
Wrap up
|
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Other International Programs
Learn more about ASH's international programs and initiatives.
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Questions?
Questions regarding the Clinical Research Training Institute in Latin America should be directed to the ASH Training Department at training@hematology.org.
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